The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008

• Published in: Journal of clinical epidemiology Vol. 63; no. 11; pp. 1179 - 1194
• Main Authors: Cella, David, Riley, William, Stone, Arthur, Rothrock, Nan, Reeve, Bryce, Yount, Susan, Amtmann, Dagmar, Bode, Rita, Buysse, Daniel, Choi, Seung, Cook, Karon, DeVellis, Robert, DeWalt, Darren, Fries, James F, Gershon, Richard, Hahn, Elizabeth A, Lai, Jin-Shei, Pilkonis, Paul, Revicki, Dennis, Rose, Matthias, Weinfurt, Kevin, Hays, Ron
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2010; Elsevier; Elsevier Limited
• Subjects: Adult; Anxiety; Biological and medical sciences; Chronic disease; Clinical outcomes; Epidemiology; Fatigue; Female; Global health; Health Status; Health Surveys; Humans; Information systems; Information Systems - standards; Internal Medicine; Item response theory; Male; Medical sciences; Miscellaneous; Outcome Assessment (Health Care) - standards; Outcome measures; Pain; Patient Satisfaction - statistics & numerical data; Patient-reported outcomes; PROMIS; Public health. Hygiene; Public health. Hygiene-occupational medicine; Quality of Life; Self Disclosure; Sleep; Surveys and Questionnaires - standards; United States; United States; Outcome measures; Patient-reported outcomes; Chronic disease; Item response theory; PROMIS; Quality of life; Human; Prognosis; Information system; Self evaluation; Theory; Patient; 2008; Chronic; 2005; Adult; Item bank; Public health
• ISSN: 0895-4356; 1878-5921
• DOI: 10.1016/j.jclinepi.2010.04.011

Abstract Objectives Patient-reported outcomes (PROs) are essential when evaluating many new treatments in health care; yet, current measures have been limited by a lack of precision, standardization, and comparability of scores across studies and diseases. The Patient-Reported Outcomes Measurement Information System (PROMIS) provides item banks that offer the potential for efficient (minimizes item number without compromising reliability), flexible (enables optional use of interchangeable items), and precise (has minimal error in estimate) measurement of commonly studied PROs. We report results from the first large-scale testing of PROMIS items. Study Design and Setting Fourteen item pools were tested in the U.S. general population and clinical groups using an online panel and clinic recruitment. A scale-setting subsample was created reflecting demographics proportional to the 2000 U.S. census. Results Using item-response theory (graded response model), 11 item banks were calibrated on a sample of 21,133, measuring components of self-reported physical, mental, and social health, along with a 10-item Global Health Scale. Short forms from each bank were developed and compared with the overall bank and with other well-validated and widely accepted (“legacy”) measures. All item banks demonstrated good reliability across most of the score distributions. Construct validity was supported by moderate to strong correlations with legacy measures. Conclusion PROMIS item banks and their short forms provide evidence that they are reliable and precise measures of generic symptoms and functional reports comparable to legacy instruments. Further testing will continue to validate and test PROMIS items and banks in diverse clinical populations.