miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells

• Published in: PloS one Vol. 17; no. 9; p. e0270364
• Main Authors: An, Xuejiao, Li, Taotao, Chen, Nana, Wang, Huihui, Su, Manchun, Shi, Huibin, Duan, Xinming, Ma, Youji
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 22.09.2022; Public Library of Science (PLoS)
• Subjects: 3' Untranslated regions; Animals; Apoptosis; Biology and Life Sciences; Energy resources; Enzymes; Genes; Genetic aspects; Glycolysis; Health aspects; Lactic acid; Metabolic pathways; Metabolism; Methods; MicroRNA; MicroRNAs; Mutation; People and Places; Proteins; Research and Analysis Methods; Sertoli cells; Sheep; Signal transduction; Signaling; Sperm; Spermatogenesis; Stem cells; Substrates; China; Gansu China

Glycolysis in Sertoli cells (SCs) can provide energy substrates for the development of spermatogenic cells. Triose phosphate isomerase 1 (TPI1) is one of the key catalytic enzymes involved in glycolysis. However, the biological function of TPI1 in SCs and its role in glycolytic metabolic pathways ar...