From Friend to Foe: Toxicity Trade-Offs Govern Staphylococcus aureus Infection Severity

The life-threatening human pathogen Staphylococcus aureus experiences an evolutionary tug-of-war between highly toxic strains, which are better able to transmit between hosts and less toxic strains which are better at infecting a single host. Read the Research Article.

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Bibliographic Details
Published inPLoS biology Vol. 13; no. 9; p. e1002230
Main Author Richardson, Lauren A
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 01.09.2015
Public Library of Science (PLoS)
Subjects
Bacteremia - microbiology
Biological Evolution
Host-bacteria relationships
Humans
Immune system
Mathematical models
Observations
Physiological aspects
Staphylococcal Infections - microbiology
Staphylococcus aureus - genetics
Staphylococcus aureus - pathogenicity
Staphylococcus aureus infections
Staphylococcus infections
Toxicity
United States
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Summary:The life-threatening human pathogen Staphylococcus aureus experiences an evolutionary tug-of-war between highly toxic strains, which are better able to transmit between hosts and less toxic strains which are better at infecting a single host. Read the Research Article.
Bibliography:The author has declared that no competing interests exist.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.1002230