Female Urinary Retention Progressing to Possible Multiple System Atrophy-cerebellar Form after 12 Years

• Published in: Internal Medicine Vol. 61; no. 23; pp. 3599 - 3604
• Main Authors: Sakakibara, Ryuji, Sekiguchi, Yuki, Panicker, Jalesh N., Sekido, Noritoshi, Sugimoto, Hideki, Sugisaki, Yuuka, Shimizu, Ayami, Takahashi, Osamu, Ogata, Tsuyoshi, Sawai, Setsu, Tateno, Fuyuki, Aiba, Yosuke, Simeoni, Sara
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.12.2022; Japan Science and Technology Agency
• Subjects: Aged; Atrophy; Autonomic nervous system; Autonomic Nervous System Diseases; Case Report; Cerebellar ataxia; Cerebellum; Cerebellum - diagnostic imaging; Electromyography; Female; Humans; Hyperactivity; Internal medicine; magnetic resonance imaging; multiple system atrophy; Multiple System Atrophy - complications; Multiple System Atrophy - diagnosis; sacral autonomic disorder; Sacrum; Sphincter; sphincter electromyography; Urinary Bladder Diseases; urinary retention; Urinary Retention - etiology; Urodynamics; sphincter electromyography; magnetic resonance imaging; multiple system atrophy; sacral autonomic disorder; urinary retention
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.8724-21

We herein report a 73-year-old Japanese woman with possible multiple system atrophy-cerebellar form (MSA-C) who suffered from urinary retention (sacral autonomic disorder) for 12 years before exhibiting cerebellar ataxia. A peculiar combination of findings on urodynamics and sphincter electromyography (EMG), e.g. detrusor hyperactivity with impaired contraction (DHIC), detrusor-sphincter dyssynergia (DSD) and neurogenic sphincter EMG (upper and lower neuron-type autonomic dysfunction), seems to have been predictive of future development of MSA.