Cardio-Ankle Vascular Index is a predictor of cardiovascular events

• Published in: Artery research Vol. 5; no. 3; pp. 91 - 96
• Main Authors: Kubota, Yoshiaki, Maebuchi, Daisuke, Takei, Makoto, Inui, Yumiko, Sudo, Yuumi, Ikegami, Yukinori, Fuse, Jun, Sakamoto, Munehisa, Momiyama, Yukihiko
• Format: Journal Article
• Language: English
• Published: Dordrecht Elsevier B.V 2011; Springer Netherlands; Springer Nature B.V; BMC
• Subjects: Atherosclerosis; Cardiovascular; Cardiovascular events; CAVI; Research Article; Cardiovascular events; CAVI; Atherosclerosis
• ISSN: 1872-9312; 1876-4401; 1876-4401
• DOI: 10.1016/j.artres.2011.03.005

The Cardio-Ankle Vascular Index (CAVI) was established as a parameter of atherosclerosis that does not depend on a subject’s blood pressure, and is now used in many centers. However, it remains unclear whether the CAVI can predict the development and outcome of cardiovascular disease. CAVI was measured as a parameter of atherosclerosis in 400 patients between January 1 and December 31, 2006. The 400 patients were classified into 3 groups according to the CAVI score: Groups A (CAVI < 9), B (9 ≤ CAVI < 10), and C (CAVI ≥ 10). The cumulative incidences of cardiovascular diseases and stroke were higher in Group C than in Group A and the log-rank test revealed a statistically significant difference between these groups ( p < 0.05). A multivariate analysis showed that the hazard ratio of cardiovascular diseases was significantly higher in Group C (hazard ratio, 2.2). In conclusion, CAVI is a useful parameter of atherosclerosis in high-risk patients and is an accurate predictor of patients at a higher risk for cardiovascular diseases.