Genetic Characterization of Extensively Drug-Resistant Shigella sonnei Infections, Spain, 2021–2022

• Published in: Emerging infectious diseases Vol. 29; no. 11; pp. 2370 - 2373
• Main Authors: Jacqueline, Camille, Carrascoso, Guillermo Ruiz, Gutierrez-Fernandez, Jose, Rangel, Teresa Vicente, Goterris, Lidia, Valdes, Fernando Vazquez, Vecilla, Domingo Fernandez, Lopez, Matilde Elia, Ruiz, Maria Rocio Martinez, Sancho, Carmen Aspiroz, Tanoira, Ramon Perez, Quilez, Elia Sirvent, de la Rica Martinez, Alba, Jimenez, Nieves Gonzalo, Salguero, Cristina Garcia, Barbera, Eva Gonzalez, Florez, Maria Reyes Sanchez, Merino, Francisco J, Redondo, Begona Sagardia, Guerrero, Enrique Rodriguez, Gonzalez, Claudia Sanz, Herrera-Leon, Silvia
• Format: Journal Article
• Language: English
• Published: Atlanta U.S. National Center for Infectious Diseases 01.11.2023; Centers for Disease Control and Prevention
• Subjects: Antibiotics; Antimicrobial agents; bacteria; Development and progression; Disease prevention; Dispatch; Drug resistance; Drug resistance in microorganisms; Drug therapy; Epidemiology; Females; Food contamination & poisoning; Genetic aspects; Genetic Characterization of Extensively Drug-Resistant; Genetic diversity; Genomes; Genotype; Health aspects; Identification and classification; Infections; Infections, Spain, 2021–2022; Metronidazole; Microbiology; Patients; sexual transmission; Shigella sonnei; Shigellosis; Spain; Surveillance; Spain; United Kingdom; United Kingdom > UK; Europe
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2911.221746

In 2022, the United Kingdom reported an increase in drug resistance in Shigella sonnei isolates. We report 33 cases in Spain genetically related to the UK cases and 4 cases with similar antimicrobial resistance profiles infected with genetically distant strains. Our results suggest circulation of multiple genetic clusters of multidrug-resistant S. sonnei in Spain.