Severe allergic contact dermatitis due to Polysporin

A healthy 28-year-old woman with a history of herpes labialis and atopic dermatitis was seen by the dermatology department after three days of substantially pruritic and edematous erythematous lip plaques with vesicles, which caused difficulty in eating and drinking. She also had a vesicular eruptio...

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Published inCanadian Medical Association journal (CMAJ) Vol. 189; no. 31; p. E1018
Main Authors Colantonio, Sophia, Kirshen, Carly
Format Journal Article
LanguageEnglish
Published Canada Joule Inc 08.08.2017
CMA Impact, Inc
Subjects
Adult
Allergies
Antibiotics
Atopic dermatitis
Bacitracin - adverse effects
Care and treatment
Complications and side effects
Dermatitis
Dermatitis, Allergic Contact - diagnosis
Dermatitis, Allergic Contact - etiology
Dermatology
Development and progression
Drug Combinations
Eczema
Female
Gramicidin - adverse effects
Humans
Occupational hazards
Polymyxin B - adverse effects
Polymyxins
Practice
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Summary:A healthy 28-year-old woman with a history of herpes labialis and atopic dermatitis was seen by the dermatology department after three days of substantially pruritic and edematous erythematous lip plaques with vesicles, which caused difficulty in eating and drinking. She also had a vesicular eruption on her left fourth finger. Allergic contact dermatitis is a delayed type IV hypersensitivity reaction that requires sensitization to a chemical agent before eliciting an eczematous reaction. In its acute phase, allergic contact dermatitis presents as well-dermarcated eczematous papules and plaques that can be edematous and vesiculobullous at the site of exposure. The prevalence of allergic contact dermatitis from topical antibiotics in the general population is unknown; many cases are mild and patients do not seek care.
Bibliography:ObjectType-Case Study-2
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ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.161214