Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report

Yellow fever vaccine exists for over 80 years and is considered to be relatively safe. However, in rare cases it can produce serious neurotropic and viscerotropic complications. We report a case of a patient who presented both viscerotropic and neurological manifestations after yellow fever vaccinat...

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Published inBMC infectious diseases Vol. 20; no. 1; p. 116
Main Authors Volkov, Lev, Grard, Gilda, Bollaert, Pierre-Edouard, Durand, Guillaume A, Cravoisy, Aurélie, Conrad, Marie, Nace, Lionel, Courte, Guilhem, Marnai, Rémy, Leparc-Goffart, Isabelle, Gibot, Sébastien
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 10.02.2020
BioMed Central
BMC
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Summary:Yellow fever vaccine exists for over 80 years and is considered to be relatively safe. However, in rare cases it can produce serious neurotropic and viscerotropic complications. We report a case of a patient who presented both viscerotropic and neurological manifestations after yellow fever vaccination. We describe the case of a 37 years old man who developed after the yellow fever vaccination a yellow fever vaccine-associated viscerotropic disease followed by acute uveitis. Prolonged detection of yellow fever RNA in blood and urine was consistent with yellow fever vaccine-associated adverse event. The final outcome was good, although with persistent fatigue over a few months. Even if the yellow fever vaccine is relatively safe, physicians should be aware of its possible serious adverse effects.
Bibliography:ObjectType-Case Study-2
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PMCID: PMC7011288
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-020-4838-x