Comparative genomics and community curation further improve gene annotations in the nematode Pristionchus pacificus

• Published in: BMC genomics Vol. 21; no. 1; pp. 708 - 9
• Main Authors: Athanasouli, Marina, Witte, Hanh, Weiler, Christian, Loschko, Tobias, Eberhardt, Gabi, Sommer, Ralf J., Rödelsperger, Christian
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.10.2020; BioMed Central; BMC
• Subjects: Amino acids; Animals; Annotations; Automation; Caenorhabditis elegans; Caenorhabditis elegans - genetics; Candidates; Comparative analysis; Datasets; Evolution; Gene families; Gene loci; Genes; Genetic aspects; Genome; Genomes; Genomics; Genotypes; Identification and classification; Invertebrates; Microbial genetics; Molecular Sequence Annotation - methods; Molecular Sequence Annotation - standards; Nematodes; Orphan genes; Parasitic nematodes; Pristionchus pacificus; Proteins; Rhabditida - genetics; Roundworms; Species; Species comparisons; Species Specificity; Worms; Germany; Parasitic nematodes; Caenorhabditis elegans; Evolution; Orphan genes; Genome

Nematode model organisms such as Caenorhabditis elegans and Pristionchus pacificus are powerful systems for studying the evolution of gene function at a mechanistic level. However, the identification of P. pacificus orthologs of candidate genes known from C. elegans is complicated by the discrepancy...