Relationship between Activity in Human Primary Motor Cortex during Action Observation and the Mirror Neuron System

• Published in: PloS one Vol. 4; no. 3; p. e4925
• Main Authors: Kilner, James M., Marchant, Jennifer L., Frith, Chris D.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.03.2009; Public Library of Science (PLoS)
• Subjects: Actors; Analysis of Variance; Arm; Attenuation; Cortex; Cortex (motor); Electroencephalography; Humans; Medical imaging; Modulation; Motor Cortex - cytology; Motor Cortex - physiology; Movement; Neurons; Neurons - physiology; Neuroscience; Neuroscience/Behavioral Neuroscience; Neuroscience/Cognitive Neuroscience; Neuroscience/Motor Systems; Neuroscience/Psychology; Oscillations; Sensorimotor system; Sensors; Studies
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0004925

The attenuation of the beta cortical oscillations during action observation has been interpreted as evidence of a mirror neuron system (MNS) in humans. Here we investigated the modulation of beta cortical oscillations with the viewpoint of an observed action. We asked subjects to observe videos of an actor making a variety of arm movements. We show that when subjects were observing arm movements there was a significant modulation of beta oscillations overlying left and right sensorimotor cortices. This pattern of attenuation was driven by the side of the screen on which the observed movement occurred and not by the hand that was observed moving. These results are discussed in terms of the firing patterns of mirror neurons in F5 which have been reported to have similar properties.