Orbital malignant melanoma associated with nevus of Ota

• Published in: Indian journal of ophthalmology Vol. 61; no. 6; pp. 306 - 309
• Main Authors: Radhadevi, Cherungottil, Charles, Kakkuzhiyil, Lathika, Vasu
• Format: Journal Article
• Language: English
• Published: India Medknow Publications 01.06.2013; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Acanthamoeba; Acanthamoeba sclerokeratitis; Acute retinal necrosis; Algorithmic approach; Angiotensin converting enzyme; antitoxoplasma antibody; Bevacizumab; Brief Communication; Cancer; Care and treatment; Case studies; Cataract surgery in uveitis; Cell Transformation, Neoplastic; Central India; Chemotherapy; choroid; choroidal neovascularization; choroidal nevus; choroidal nodules; conjunctivitis; Corticosteroids; Diagnosis; differential diagnosis; glaucoma surgery in uveitis; granulomatous inflammation; Health aspects; Humans; immunosuppression; immunosuppressive agents; immunosuppressives; laboratory test; Magnetic resonance imaging; Male; Malignant melanoma; medical management; Melanoma; Melanoma - pathology; Melanoma - surgery; Middle Aged; Mole (Dermatology); naming and meshing; Neoplasms, Second Primary - pathology; Neoplasms, Second Primary - surgery; nevus; nevus of Ota; Nevus of Ota - pathology; Nevus of Ota - surgery; ocular dirofilariasis; ocular toxoplasmosis; Oestrus ovis; Ophthalmomyiasis; Orbital Neoplasms - pathology; Orbital Neoplasms - surgery; orbitotomy; Patient outcomes; polymerase chain reaction; Risk factors; Sarcoidosis; scleritis; serpiginous choroiditis; Skin Neoplasms - pathology; Skin Neoplasms - surgery; T cells; tuberculin test; ultrasound; uveitis; Uveitis; imaging; fluorescein angiography; optical coherence tomography; vitrectomy in uveitis; India; nevus of Ota; Malignant melanoma; orbitotomy
• ISSN: 0301-4738; 1998-3689
• DOI: 10.4103/0301-4738.109526

Nevus of Ota (oculodermal melanosis) is a dermal melanocytic hamartoma with bluish hyperpigmentation along the first and second branches of the trigeminal nerve. Extracutaneous involvement, especially ocular, has been reported. A 45-year-old male presented with malignant melanoma of the left orbit in association with nevus of Ota. Being locally invasive, a modified exenteration with frontal flap repair was done on left eye. Adjuvant chemotherapy was given after wound healing. All pigmented lesions of the eye require close monitoring to help in the early diagnosis. Since malignant transformation has been reported in oculodermal melanosis, close follow-up and patient education will facilitate early diagnosis and prompt management. This case is reported for its rarity and unusual presentation.