Seroconversion of anti-Getah virus antibody among Japanese native Noma horses around 2012

• Published in: Journal of Veterinary Medical Science Vol. 84; no. 12; pp. 1605 - 1609
• Main Authors: TAKEISHI, Makoto, KUWATA, Ryusei, ONO, Tetsushi, SASAKI, Asami, OGATA, Mone, IWATA, Eri, TAJI, Syuichi, KOIKE, Masamitsu, NEMOTO, Manabu, BANNAI, Hiroshi, ISAWA, Haruhiko, MAEDA, Ken, MORIKAWA, Shigeru, KITAGAWA, Hitoshi, YOSHIKAWA, Yasuhiro
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2022; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Alphavirus; Alphavirus Infections - diagnosis; Alphavirus Infections - epidemiology; Alphavirus Infections - veterinary; Animals; Antibodies, Viral; Culicidae; Disease transmission; Edema; ELISA; Enzyme-linked immunosorbent assay; Fever; Getah virus; Horse Diseases; Horses; Japan - epidemiology; Japanese native horse; Noma - veterinary; Seroconversion; Virology; virus neutralization test; Viruses; Japan; Getah virus; virus neutralization test; Japanese native horse; ELISA
• ISSN: 0916-7250; 1347-7439; 1347-7439
• DOI: 10.1292/jvms.22-0306

Getah virus (GETV), an arthropod-borne virus transmitted by mosquitoes, has been isolated from several animals. GETV infection in horses shows clinical signs such as fever, rash, and edema in the leg. Noma horses are one of the eight Japanese native horses. The present study aimed to clarify the occurrence of GETV infection in Noma horses. Serum samples collected from Noma horses were analyzed using a virus neutralization test and enzyme-linked immunosorbent assay and showed that the anti-GETV antibody titers in the samples collected in 2017 were significantly higher than those collected in 2012. We concluded that a seroconversion of anti-GETV antibodies was occurred in the Noma horse population around 2012, providing evidence of the GETV epidemic in Japan circa 2012.