Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018

• Published in: Emerging infectious diseases Vol. 25; no. 5; pp. 1003 - 1006
• Main Authors: Yadav, Pragya D., Shete, Anita M., Kumar, G. Arun, Sarkale, Prasad, Sahay, Rima R., Radhakrishnan, Chandni, Lakra, Rajen, Pardeshi, Prachi, Gupta, Nivedita, Gangakhedkar, Raman R., Rajendran, V.R., Sadanandan, Rajeev, Mourya, Devendra T.
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.05.2019; Centers for Disease Control and Prevention
• Subjects: Analysis; Animals; Cells, Cultured; Chiroptera - virology; Cytopathogenic Effect, Viral; Disease Outbreaks; Dispatch; Genes; Genomes; Henipavirus Infections - epidemiology; Henipavirus Infections - history; Henipavirus Infections - transmission; Henipavirus Infections - virology; History, 21st Century; Human; Humans; India - epidemiology; Infection; Kerala; Medical research; Mutation; next-generation sequencing; Nipah virus; Nipah Virus - classification; Nipah Virus - genetics; Nipah Virus Sequences from Humans and Bats during Nipah Outbreak, Kerala, India, 2018; Phylogeny; Pteropus medius; Public Health Surveillance; qRT-PCR; RNA; India; Bangladesh; Malaysia; Human; viruses; next-generation sequencing; Pteropus medius; qRT-PCR; Nipah virus; Kerala; India
• ISSN: 1080-6040; 1080-6059; 1080-6059
• DOI: 10.3201/eid2505.181076

We retrieved Nipah virus (NiV) sequences from 4 human and 3 fruit bat (Pteropus medius) samples from a 2018 outbreak in Kerala, India. Phylogenetic analysis demonstrated that NiV from humans was 96.15% similar to a Bangladesh strain but 99.7%-100% similar to virus from Pteropus spp. bats, indicating bats were the source of the outbreak.