CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers

Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers. In this study, we present c...

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Published inBMC bioinformatics Vol. 19; no. 1; p. 292
Main Authors Zhong, Shanliang, Wang, Jinyan, Zhang, Qian, Xu, Hanzi, Feng, Jifeng
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 03.08.2018
BioMed Central
BMC
Subjects
Cancer
Chromosome mapping
Circular RNAs
Computational biology
Divergent primer
Gene expression
Genetic research
Genomes
Identification
Identification and classification
Methods
Molecular genetics
Post-transcription
Primers
Proteins
RNA
Scientific software
Sequence
Software
Divergent primer
Circular RNAs
Sequence
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Summary:Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers. In this study, we present circPrimer, which allows users to search, annotate, and visualize circRNAs. Additionally, circPrimer enables users to extract the spliced sequences and genomic sequences of any circRNA, including novel circRNAs. Furthermore, circPrimer help users to design primers for circRNAs and to determine the specificity of the circRNA primers. CircPrimer is a user-friendly tool for exploring circRNAs that does not require special user skills.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1471-2105
1471-2105
DOI:10.1186/s12859-018-2304-1