Subclinical avian influenza A(H5N1) virus infection in human, Vietnam

• Published in: Emerging infectious diseases Vol. 19; no. 10; pp. 1674 - 1677
• Main Authors: Le, Mai Quynh, Horby, Peter, Fox, Annette, Nguyen, Hien Tran, Le Nguyen, Hang Khanh, Hoang, Phuong Mai Vu, Nguyen, Khanh Cong, de Jong, Menno D, Jeeninga, Rienk E, Rogier van Doorn, H, Farrar, Jeremy, Wertheim, Heiman F L
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01.10.2013; Centers for Disease Control and Prevention
• Subjects: Adolescent; Adult; Amino Acid Substitution; Animals; Asymptomatic Infections; Avian influenza; avian influenza A(H5N1); Avian influenza viruses; Chickens - virology; Contact Tracing; Dispatch; Dogs; Fatal Outcome; Female; Health aspects; human; Humans; Infant; Infection; influenza; Influenza A Virus, H5N1 Subtype - genetics; Influenza in Birds - transmission; Influenza in Birds - virology; Influenza, Human - diagnosis; Influenza, Human - transmission; Influenza, Human - virology; Madin Darby Canine Kidney Cells; Male; Middle Aged; Molecular Diagnostic Techniques; Phylogeny; Polymerase Chain Reaction; Public health; subclinical; Vietnam; viruses; Zoonoses; Vietnam; influenza; H5N1; Vietnam; poultry; subclinical; viruses; avian influenza; avian influenza A(H5N1); clades; asymptomatic; human
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid1910.130730

Laboratory-confirmed cases of subclinical infection with avian influenza A(H5N1) virus in humans are rare, and the true number of these cases is unknown. We describe the identification of a laboratory-confirmed subclinical case in a woman during an influenza A(H5N1) contact investigation in northern Vietnam.