Non-opioid Analgesics and the Endocannabinoid System

• Published in: Balkan medical journal Vol. 37; no. 6; pp. 309 - 315
• Main Authors: Topuz, Ruhan Deniz, Gündüz, Özgur, Karadağ, Çetin Hakan, Ulugöl, Ahmet
• Format: Journal Article
• Language: English
• Published: Galenos Yayinevi Tic. Ltd 01.11.2020; Trakya Üniversitesi; Galenos Publishing; Galenos Publishing House
• Subjects: Acetaminophen; dipyrone; Endocannabinoids; Health aspects; Invited Review; Nonsteroidal anti-inflammatory agents; nsaids; paracetamol; Physiological aspects; Tıp; Turkey; Türkiye; Edirne; Dipyrone; endocannabinoids; paracetamol; NSAIDs

Non-steroidal anti-inflammatory drugs produce antinociceptive effects mainly through peripheral cyclooxygenase inhibition. In opposition to the classical non-steroidal anti-inflammatory drugs, paracetamol and dipyrone exert weak anti-inflammatory activity, their antinociceptive effects appearing to...