Detection of Dengue Virus among Children with Suspected Malaria, Accra, Ghana

We report new molecular evidence of locally acquired dengue virus infections in Ghana. We detected dengue viral RNA among children with suspected malaria by using a multipathogen real-time PCR. Subsequent sequence analysis revealed a close relationship with dengue virus serotype 2, which was implica...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 24; no. 8; pp. 1544 - 1547
Main Authors Amoako, Nicholas, Duodu, Samuel, Dennis, Francis E, Bonney, Joseph H K, Asante, Kwaku P, Ameh, Juliana, Mosi, Lydia, Hayashi, Takaya, Agbosu, Eudosia E, Pratt, Deborah, Operario, Darwin J, Fields, Barry, Liu, Jie, Houpt, Eric R, Armah, George E, Stoler, Justin, Awandare, Gordon A
Format Journal Article
LanguageEnglish
Published United States U.S. National Center for Infectious Diseases 01.08.2018
Centers for Disease Control and Prevention
Subjects
Adolescent
Care and treatment
Child
Child, Preschool
children
Coinfection
Cross-Sectional Studies
Dengue
Dengue - epidemiology
Dengue - virology
Dengue virus
Dengue Virus - classification
Dengue Virus - genetics
Dengue Virus - isolation & purification
Development and progression
Dispatch
DNA, Protozoan - genetics
DNV2
febrile illness
Female
Ghana - epidemiology
Health aspects
Humans
Infant
Infant, Newborn
Infection
Malaria
Malaria - epidemiology
Malaria - parasitology
Male
Multipathogen Assay for Detection of Dengue Virus among Children with Suspected Malaria, Accra, Ghana
Plasmodium - classification
Plasmodium - genetics
Plasmodium - isolation & purification
Real-Time Polymerase Chain Reaction
RNA, Viral - genetics
Serogroup
TaqMan array card
Ghana
Nigeria
Burkina Faso
viruses
Kintampo
DNV2
Dengue
endemic
Ghana
malaria
febrile illness
co-infected
multi-pathogen
Plasmodium
Accra
assay
children
West Africa
TaqMan array card
malaria parasitemia
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Summary:We report new molecular evidence of locally acquired dengue virus infections in Ghana. We detected dengue viral RNA among children with suspected malaria by using a multipathogen real-time PCR. Subsequent sequence analysis revealed a close relationship with dengue virus serotype 2, which was implicated in a 2016 outbreak in Burkina Faso.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid2408.180341