Prognostic Factors of Wilms' Tumor Complicated with Nephroblastomatosis

Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblast...

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Published inChinese medical journal Vol. 128; no. 18; pp. 2539 - 2541
Main Authors Niu, Hong-Chuan, Zhang, Wei-Ping, Sun, Ning, He, Le-Jian, Peng, Yun
Format Journal Article
LanguageEnglish
Published China Medknow Publications Pvt Ltd 20.09.2015
Medknow Publications and Media Pvt. Ltd
Lippincott Williams & Wilkins Ovid Technologies
Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China%Department of Pathology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China%Imaging Center, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China
Medknow Publications & Media Pvt Ltd
Wolters Kluwer
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Summary:Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblastomatosis were known as precursor lesions of Wilms tumor,Nephroblastomatosis can be classified into four categories: Perilobar (PEN R only); i ntralobar (I LNR only); combined (PLNR and ILNR); and universal. The diagnosis and treatment of Wilms" tumor have been improved constantly and achieved common sense. However, little information is available regarding Wilms" tumor associated with nephroblastomatosis for lower prevalence. This study aimed to investigate the prognostic factors of Wilms' tumor associated with nephroblastomatosis.
Bibliography:Multicentric Lesions; Nephroblastomatosis; Prognostic Factors; Wilms Tumor
11-2154/R
Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblastomatosis were known as precursor lesions of Wilms tumor,Nephroblastomatosis can be classified into four categories: Perilobar (PEN R only); i ntralobar (I LNR only); combined (PLNR and ILNR); and universal. The diagnosis and treatment of Wilms" tumor have been improved constantly and achieved common sense. However, little information is available regarding Wilms" tumor associated with nephroblastomatosis for lower prevalence. This study aimed to investigate the prognostic factors of Wilms' tumor associated with nephroblastomatosis.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0366-6999
2542-5641
DOI:10.4103/0366-6999.164985