Prognostic Factors of Wilms' Tumor Complicated with Nephroblastomatosis
Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblast...
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Published in | Chinese medical journal Vol. 128; no. 18; pp. 2539 - 2541 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
China
Medknow Publications Pvt Ltd
20.09.2015
Medknow Publications and Media Pvt. Ltd Lippincott Williams & Wilkins Ovid Technologies Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China%Department of Pathology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China%Imaging Center, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China Medknow Publications & Media Pvt Ltd Wolters Kluwer |
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Summary: | Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblastomatosis were known as precursor lesions of Wilms tumor,Nephroblastomatosis can be classified into four categories: Perilobar (PEN R only); i ntralobar (I LNR only); combined (PLNR and ILNR); and universal. The diagnosis and treatment of Wilms" tumor have been improved constantly and achieved common sense. However, little information is available regarding Wilms" tumor associated with nephroblastomatosis for lower prevalence. This study aimed to investigate the prognostic factors of Wilms' tumor associated with nephroblastomatosis. |
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Bibliography: | Multicentric Lesions; Nephroblastomatosis; Prognostic Factors; Wilms Tumor 11-2154/R Nephrogenic rests (NRs) are abnormally persistent clusters of embryonal cells, representing microscopic dysplasias of the developing kidney. NRs are found in approximately 1% of infant kidneys at autopsy. Nephroblastomatosis signifies the presence of multiple or diffuse NRs. Both NRs and nephroblastomatosis were known as precursor lesions of Wilms tumor,Nephroblastomatosis can be classified into four categories: Perilobar (PEN R only); i ntralobar (I LNR only); combined (PLNR and ILNR); and universal. The diagnosis and treatment of Wilms" tumor have been improved constantly and achieved common sense. However, little information is available regarding Wilms" tumor associated with nephroblastomatosis for lower prevalence. This study aimed to investigate the prognostic factors of Wilms' tumor associated with nephroblastomatosis. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0366-6999 2542-5641 |
DOI: | 10.4103/0366-6999.164985 |