Recent advances in immunoassays and biosensors for mycotoxins detection in feedstuffs and foods

• Published in: Journal of animal science and biotechnology Vol. 12; no. 1; p. 108
• Main Authors: Li, Runxian, Wen, Yang, Wang, Fenglai, He, Pingli
• Format: Journal Article
• Language: English
• Published: England BioMed Central 11.10.2021; BMC
• Subjects: animals; Antibodies; Antigens; Biosensors; Carcinogens; Cereals; Chromatography; Contamination; Enzymes; feed contamination; feeds; Food; Food safety; fungi; Immunoassay; Immunoassays; Interdisciplinary subjects; Medical diagnosis; Medical research; Metabolites; Methods; Multiple detection; Mycotoxins; Nanomaterials; Nanotechnology; Polymers; Rapid detection; rapid methods; Review; Secondary metabolites; Sensors; Signal transduction; species; toxicity; Multiple detection; Nanomaterials; Biosensors; Rapid detection; Immunoassays; Mycotoxins
• ISSN: 2049-1891; 1674-9782; 2049-1891
• DOI: 10.1186/s40104-021-00629-4

Mycotoxins are secondary metabolites produced by fungus. Many mycotoxin species are highly toxic and are frequently found in cereals and feedstuffs. So, powerful detection methods are vital and effective ways to prevent feed contamination. Traditional detection methods can no longer meet the needs of massive, real-time, simple, and fast mycotoxin monitoring. Rapid detection methods based on advanced material and sensor technology are the future trend. In this review, we highlight recent progress of mycotoxin rapid detection strategies in feedstuffs and foods, especially for simultaneous multiplex mycotoxin determination. Immunoassays, biosensors, and the prominent roles of nanomaterials are introduced. The principles of different types of recognition and signal transduction are explained, and the merits and pitfalls of these methods are compared. Furthermore, limitations and challenges of existing rapid sensing strategies and perspectives of future research are discussed.