Caste development and reproduction: a genome-wide analysis of hallmarks of insect eusociality

The honey bee queen and worker castes are a model system for developmental plasticity. We used established expressed sequence tag information for a Gene Ontology based annotation of genes that are differentially expressed during caste development. Metabolic regulation emerged as a major theme, with...

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Published inInsect molecular biology Vol. 15; no. 5; pp. 703 - 714
Main Authors Cristino, A.S, Nunes, F.M.F, Lobo, C.H, Bitondi, M.M.G, Simões, Z.L.P, Fontoura Costa, L. da, Lattorff, H.M.G, Moritz, R.F.A, Evans, J.D, Hartfelder, K
Format Journal Article
LanguageEnglish
Published Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.10.2006
Blackwell Publishing Ltd
Subjects
AlignACE
Animals
Apis mellifera
Bees - genetics
caste determination
caste development
caste genes
differential gene expression
expressed sequence tags
gene annotation
gene expression
Gene Expression Regulation, Developmental
gene ontology
genome
Genome, Insect
honey bees
insect castes
insect reproduction
insect sociobiology
meiosis
oogenesis
Oogenesis - genetics
Reproduction - genetics
reproductive division of labor
sequence analysis
Social Behavior
Special Issue: The Honey Bee Genome
UCR motifs
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Summary:The honey bee queen and worker castes are a model system for developmental plasticity. We used established expressed sequence tag information for a Gene Ontology based annotation of genes that are differentially expressed during caste development. Metabolic regulation emerged as a major theme, with a caste-specific difference in the expression of oxidoreductases vs. hydrolases. Motif searches in upstream regions revealed group-specific motifs, providing an entry point to cis-regulatory network studies on caste genes. For genes putatively involved in reproduction, meiosis-associated factors came out as highly conserved, whereas some determinants of embryonic axes either do not have clear orthologs (bag of marbles, gurken, torso), or appear to be lacking (trunk) in the bee genome. Our results are the outcome of a first genome-based initiative to provide an annotated framework for trends in gene regulation during female caste differentiation (representing developmental plasticity) and reproduction.
Bibliography:http://dx.doi.org/10.1111/j.1365-2583.2006.00696.x
http://hdl.handle.net/10113/28353
ArticleID:IMB696
istex:599853876D9FC600B43733DBFF7096B3416CC30D
ark:/67375/WNG-FHZ1753C-6
Re‐use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitation.
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Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitation.
ISSN:0962-1075
1365-2583
DOI:10.1111/j.1365-2583.2006.00696.x