Neurocysticercosis: HP10 antigen detection is useful for the follow-up of the severe patients

• Published in: PLoS neglected tropical diseases Vol. 7; no. 3; p. e2096
• Main Authors: Fleury, Agnès, Garcia, Esperanza, Hernández, Marisela, Carrillo, Roger, Govezensky, Tzipe, Fragoso, Gladis, Sciutto, Edda, Harrison, Leslie J S, Parkhouse, R Michael Evans
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.03.2013; Public Library of Science (PLoS)
• Subjects: Accuracy; Adult; Aged; Antigens; Antigens, Helminth; Antigens, Helminth - analysis; Antigens, Helminth - blood; Antigens, Helminth - cerebrospinal fluid; Biological Markers; Biomarkers - analysis; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Brain; Brain - diagnostic imaging; Cerebrospinal fluid; Clinical Laboratory Techniques; Clinical Laboratory Techniques - economics; Clinical Laboratory Techniques - methods; Cohort Studies; Confidence intervals; Cysticercosis; Diagnosis; Drug Monitoring; Drug Monitoring - economics; Drug Monitoring - methods; Enzyme-Linked Immunosorbent Assay; Enzyme-Linked Immunosorbent Assay - economics; Enzyme-Linked Immunosorbent Assay - methods; Evolution; Female; Humans; Life Sciences; Longitudinal Studies; Magnetic Resonance Imaging; Male; Medical imaging; Medicine; Methods; Middle Aged; Neurocysticercosis; Neurocysticercosis - diagnosis; Neurocysticercosis - drug therapy; NMR; Nuclear magnetic resonance; Parasites; Parasitic diseases; Parasitology; Parasitology - economics; Parasitology - methods; Patients; Properties; Prospective Studies; Radiography; Randomized Controlled Trials as Topic; Santé publique et épidémiologie; Studies; Substance abuse treatment; Mexico; Brain; Antigens, Helminth; Parasitology; Prospective Studies; Enzyme-Linked Immunosorbent Assay; Biological Markers; Clinical Laboratory Techniques; Humans; Middle Aged; Male; Neurocysticercosis; Randomized Controlled Trials as Topic; Magnetic Resonance Imaging; Adult; Female; Aged; Drug Monitoring; Longitudinal Studies; Cohort Studies

The most severe clinical form of neurocysticercosis (NC) occurs when cysticerci are located in the subarachnoid space at the base of the brain (SaB). The diagnosis, monitoring and treatment of NC-SaB, constitutes a severe clinical challenge. Herein we evaluate the potential of the HP10 antigen detec...