Safety Assessment of Canola Oil Extracted by Aid of Pulsed Electric Field: Genetic, Acute and Subacute Toxicity

Pulsed electric field (PEF) is a nonthermal technology resulting in the rupture of cell membranes and increasing the electrical conductivity and the permeability of intracellular material. There was little work about the safety of food treated by PEF. The acute, subacute oral, and genetic toxicities...

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Bibliographic Details
Published inJournal of Oleo Science Vol. 71; no. 7; pp. 959 - 974
Main Authors Li, Qian, Li, Yong-Lian, Wang, Xin-Ying, He, Xu-Dong, Qian, Jian-Ya
Format Journal Article
LanguageEnglish
Published Japan Japan Oil Chemists' Society 01.01.2022
Japan Science and Technology Agency
Subjects
Abnormalities
Atherosclerosis
Canola oil
Cell membranes
Electric fields
Electrical resistivity
Food
Health services
pulsed electric field
safety assessment
Signs and symptoms
toxicity
Toxicity testing
safety assessment
toxicity
canola oil
pulsed electric field
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Summary:Pulsed electric field (PEF) is a nonthermal technology resulting in the rupture of cell membranes and increasing the electrical conductivity and the permeability of intracellular material. There was little work about the safety of food treated by PEF. The acute, subacute oral, and genetic toxicities were investigated to explore the safety of canola oil extracted by aid of PEF treatment (PTCO). The results showed that no negative consequences were caused by PEF. PTCO was regarded as practically non-toxic with a LD50 higher than 40 g/kg bw. No oil intake-related mortality, clinical, weight gain and organ coefficient abnormalities were observed. The histopathological symptoms indicated a mild load but not obvious toxicities on liver and kidney. The 28-day subacute toxicity test confirmed that less than 10 g/kg·d bw of oil intake did not exhibit any intake-related changes in physical, physiological, biochemical, hematological, and histopathological signs. The less than 4 of atherosclerosis index suggested that no risk of cardiovascular disease caused by PTCO intake. It was speculated that the PEF treatment would not cause any safety issues to food products.
ISSN:1345-8957
1347-3352
DOI:10.5650/jos.ess21445