“Broad” consent, exceptions to consent and the question of using biological samples for research purposes different from the initial collection purpose

• Published in: Social science & medicine (1982) Vol. 70; no. 2; pp. 217 - 220
• Main Author: Petrini, Carlo
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 2010; Elsevier; Pergamon Press Inc
• Series: Social Science & Medicine
• Subjects: Biobanks; Bioethical Issues; Bioethics; Biological and medical sciences; Biological Specimen Banks - ethics; Biomedical Research - ethics; Broad consent; Conflict; Conflict of Interest; Consent; Ethics; Europe; Human body; Humans; Informed consent; Informed Consent - ethics; Informed Consent - legislation & jurisprudence; Informed consent Biobanks Ethics Research Broad consent; Jurisprudence; Medical ethics; Medical research; Medical sciences; Miscellaneous; Professional Ethics; Public health. Hygiene; Public health. Hygiene-occupational medicine; Scientific research; Teaching. Deontology. Ethics. Legislation; Tissue Donors; Europe; Ethics; Informed consent; Research; Broad consent; Biobanks; Human; Tissue bank; Scientific research; Biology; Social medicine; Public health
• ISSN: 0277-9536; 1873-5347; 1873-5347
• DOI: 10.1016/j.socscimed.2009.10.004

An important ethical issue regarding biological samples stored in biobanks is unforeseen future sample use, when no or limited subject consent is obtained. Biobanks of biological samples have significant future research potential, but may cause conflicts of interest regarding the consent obtained. Indeed, ethics, deontology, and jurisprudence generally advise that consent must be specific and circumstantiated. However, it is not possible to foresee all of the future circumstances in which the samples might be useful, nor is it possible to re-contact all subjects in order to gain consent for a new use. The main arguments for the use of “broad” consent are presented with a brief discussion of the conditions where it may be legitimate not to obtain consent. Particular attention is given to the expressed positions of national and international bioethics bodies.