Correlation between maternal serum antibodies and protection against bovine rotavirus diarrhea in calves

• Published in: Journal of Veterinary Medical Science Vol. 62; no. 2; pp. 219 - 221
• Main Authors: Kohara, J. (Hokkaido. Shintoku Animal Husbandry Experiment Station (Japan)), Tsunemitsu, H
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.02.2000; Japan Science and Technology Agency
• Subjects: Animals; ANTIBODIES; Antibodies, Viral - blood; ANTICORPS; ANTICUERPOS; BLOOD SERUM; BOVIN; bovine rotavirus; calf; CALVES; CATTLE; Cattle Diseases - immunology; DIARREA; diarrhea; Diarrhea - immunology; Diarrhea - veterinary; Diarrhea - virology; DIARRHEE; DIARRHOEA; Female; GANADO BOVINO; IMMUNITE MATERNELLE; Immunity, Maternally-Acquired - immunology; INMUNIDAD MATERNAL; MATERNAL IMMUNITY; Neutralization Tests - veterinary; Pregnancy; ROTAVIRUS; Rotavirus - immunology; Rotavirus Infections - immunology; Rotavirus Infections - veterinary; SERUM SANGUIN; SUERO SANGUINEO; TERNERO; VEAU
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.62.219

The correlation between maternal serum antibodies in beef calves at 2 days old and protection against diarrhea induced by natural bovine rotavirus (BRV) infection was examined. Virus neutralizing (VN) antibody liters against BRV in sera from calves that developed diarrhea by BRV infection within 14 days of age (BRV-diarrheal calves) were significantly lower than those from calves that had no diarrhea. In the BRV-diarrheal calves, a positive correlation was found between the VN antibody liters and age of the onset of diarrhea. There were negative correlations between the VN antibody liters and duration of the diarrhea, VN antibody titers and cumulative diarrhea scores, and the VN antibody liters and duration of virus shedding. These results suggest that the VN antibody liters against BRV in newborn calf serum could be an indicator of protection against BRV-induced diarrhea