Surgical Management of Minimally Invasive Anterior Lumbar Interbody Fusion With Stand-Alone Interbody Cage for L4-5 Degenerative Disorders: Clinical and Radiographic Findings

• Published in: Neurologia medico-chirurgica Vol. 53; no. 12; pp. 861 - 869
• Main Authors: HIRONAKA, Yasuo, MORIMOTO, Tetsuya, MOTOYAMA, Yasushi, PARK, Young-Su, NAKASE, Hiroyuki
• Format: Journal Article
• Language: English
• Published: Japan The Japan Neurosurgical Society 2013
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; anterior lumbar interbody fusion; Blood Loss, Surgical; circumferential fusion; degenerative lumbar spinal disorder; Female; Humans; Internal Fixators; Intervertebral Disc Degeneration - diagnostic imaging; Intervertebral Disc Degeneration - surgery; Length of Stay - statistics & numerical data; Lordosis - pathology; Low Back Pain - etiology; Lumbar Vertebrae - diagnostic imaging; Lumbar Vertebrae - surgery; Male; Middle Aged; Minimally Invasive Surgical Procedures - instrumentation; Minimally Invasive Surgical Procedures - methods; minimally invasive therapy; Operative Time; Original; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Radiography; Retrospective Studies; Sciatica - etiology; Spinal Fusion - instrumentation; Spinal Fusion - methods; Spinal Stenosis - diagnostic imaging; Spinal Stenosis - surgery; Spondylolisthesis - diagnostic imaging; Spondylolisthesis - surgery; Young Adult
• ISSN: 0470-8105; 1349-8029
• DOI: 10.2176/nmc.oa2012-0379

Surgical treatment for degenerative spinal disorders is controversial, although lumbar fusion is considered an acceptable option for disabling lower back pain. Patients underwent instrumented minimally invasive anterior lumbar interbody fusion (mini-ALIF) using a retroperitoneal approach except for requiring multilevel fusions, severe spinal canal stenosis, high-grade spondylolisthesis, and a adjacent segments disorders. We retrospectively reviewed the clinical records and radiographs of 142 patients who received mini-ALIF for L4-5 degenerative lumbar disorders between 1998 and 2010. We compared preoperative and postoperative clinical data and radiographic measurements, including the modified Japanese Orthopaedic Association (JOA) score, visual analog scale (VAS) score for back and leg pain, disc height (DH), whole lumbar lordosis (WL), and vertebral wedge angle (WA). The mean follow-up period was 76 months. The solid fusion rate was 90.1% (128/142 patients). The average length of hospital stay was 6.9 days (range, 3–21 days). The mean blood loss was 63.7 ml (range, 10–456 ml). The mean operation time was 155.5 min (range, 96–280 min). The postoperative JOA and VAS scores for back and leg pain were improved compared with the preoperative scores. Radiological analysis showed significant postoperative improvements in DH, WL, and WA, and the functional and radiographical outcomes improved significantly after 2 years. The 2.8% complication rate included cases of wound infection, liquorrhea, vertebral body fractures, and a misplaced cage that required revision. Mini-ALIF was found to be associated with improved clinical results and radiographic findings for L4-5 disorders. A retroperitoneal approach might therefore be a valuable treatment option.