Renal dysplasia in a Shih Tzu dog in Japan

• Published in: Journal of Veterinary Medical Science Vol. 63; no. 10; pp. 1127 - 1130
• Main Authors: Ohara, K. (Ohara Animal Hospital, Shinshiro, Aichi (Japan)), Kobayashi, Y, Tsuchiya, N, Furuoka, H, Matsui, T
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.10.2001; Japan Science and Technology Agency
• Subjects: Animals; BREEDS (ANIMALS); canine; Dog Diseases - drug therapy; Dog Diseases - pathology; DOGS; Fatal Outcome; Fibrosis - pathology; Glucocorticoids - therapeutic use; Histocytochemistry - veterinary; JAPAN; Kidney - pathology; KIDNEY DISEASES; Kidney Failure, Chronic - drug therapy; Kidney Failure, Chronic - pathology; Kidney Failure, Chronic - veterinary; Male; renal dysplasia; Shih Tzu; Japan
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.63.1127

A 5-month-old, male, Shih Tzu dog manifesting polyuria and polydipsia since 2-month-old was presented to our hospital with additional clinical complaints of vomiting and depression during recent a few days. Despite the symptomatic therapy for chronic renal failure, he died on the day after medication. Macroscopically, both kidneys were small in size with rough surface. Microscopical examination revealed bilateral renal fibrosis with dysplastic changes consisting of immature glomeruli and tubules, and foci of adenomatoid proliferation of tubular epithelium. In addition, incomplete lobulation of medulla with pelvic structures was also noticed in the right kidney. From these findings, the present case was diagnosed as renal dysplasia in Shih Tzu dog which was documented in the literatures.