Potentials to alleviate coagulopathy and enhance microglial function of beta (β)- glucans, making them worth a clinical study for COVID-19's neurological sequalae

•Neurological implications of COVID-19 directly correlate with neural inflammation.•Clotting dysregulation following inflammation leads to stroke and hemorrhage.•Scavengers like microglia handle the clearing of damages caused by inflammation.•β-Glucans by rejuvenating microglia, help attenuate post-...

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Published inJournal of the Neurological Sciences Vol. 427; p. 117554
Main Authors Raghavan, Kadalraja, Kandaswamy, Ramesh Shankar, Ikewaki, Nobunao, Iwasaki, Masaru, Abraham, Samuel J.K.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.08.2021
Elsevier BV
Subjects
Beta glucan
beta-Glucans
COVID-19
Humans
Letter to the Editor
Microglia
Neurological sequalae
Neurology
Nutritional supplement
SARS-CoV-2
COVID-19
Neurological sequalae
Nutritional supplement
Beta glucan
Microglia
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Summary:•Neurological implications of COVID-19 directly correlate with neural inflammation.•Clotting dysregulation following inflammation leads to stroke and hemorrhage.•Scavengers like microglia handle the clearing of damages caused by inflammation.•β-Glucans by rejuvenating microglia, help attenuate post-COVID neuroinflammation.•Study on β-Glucans as prophylaxis to COVID-19 is worthy for its beneficial effects.
Bibliography:content type line 23
SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
ISSN:0022-510X
1878-5883
1878-5883
DOI:10.1016/j.jns.2021.117554