The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction

• Published in: Annals of pediatric cardiology Vol. 5; no. 1; pp. 27 - 33
• Main Authors: Holmes, Anthony A, Co, Steve, Human, Derek G, Leblanc, Jacques G, Campbell, Andrew Im
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.01.2012; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Care and treatment; Children & youth; Contegra; Diagnosis; Endovascular stents; Heart; Heart ventricle, Right; Mortality; Original; outcome; Physiological aspects; pulmonary; Pulmonary arteries; Pulmonary artery; Pulmonary stenosis; reintervention; risk factor; Risk factors; Surgery; Transplants & implants; Veins & arteries; India; pulmonary; Contegra; reintervention; risk factor; outcome
• ISSN: 0974-2069; 0974-5149
• DOI: 10.4103/0974-2069.93706

To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12-16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12-16 mm.