Cyclodextrin-Based Supramolecular Assemblies and Hydrogels: Recent Advances and Future Perspectives

• Published in: Macromolecular rapid communications. Vol. 35; no. 13; pp. 1166 - 1184
• Main Authors: Tan, Shereen, Ladewig, Katharina, Fu, Qiang, Blencowe, Anton, Qiao, Greg G.
• Format: Journal Article
• Language: English
• Published: Weinheim Blackwell Publishing Ltd 01.07.2014; Wiley; Wiley Subscription Services, Inc
• Subjects: Actuators; Antibiotics, Antineoplastic - chemistry; Applied sciences; Assemblies; Binding sites; Cadmium; Crosslinking; cyclodextrin; Cyclodextrins; Cyclodextrins - chemistry; Drug Carriers - chemistry; Exact sciences and technology; Fabrication; host-guest chemistry; Hydrogels; Hydrogels - chemistry; Micelles; Natural polymers; Physicochemistry of polymers; Polymers - chemistry; R&D; Research & development; Starch and polysaccharides; supramolecular chemistry; Water - chemistry; Colloidal gel; Cyclodextrin; State of the art; Inclusion polymer; Physical gel; Oside polymer; Polymer; hydrogels; host-guest chemistry; supramolecular chemistry; Rotaxane; cyclodextrin
• ISSN: 1022-1336; 1521-3927; 1521-3927
• DOI: 10.1002/marc.201400080

The application of cyclodextrin (CD)‐based host–guest interactions towards the fabrication of functional supramolecular assemblies and hydrogels is of particular interest in the field of biomedicine. However, as of late they have found new applications as advanced functional materials (e.g., actuators and self‐healing materials), which have renewed interest across a wide range of fields. Advanced supramolecular materials synthesized using this noncovalent interaction, exhibit specificity and reversibility, which can be used to impart reversible cross‐linking, specific binding sites, and functionality. In this review, various functional CD‐based supramolecular assemblies and hydrogels will be outlined with the focus on recent advances. In addition, an outlook will be provided on the direction of this rapidly developing field. In this review, the application of cyclodextrin (CD)‐based host–guest interactions towards the fabrication of functional supramolecular assemblies and hydrogels is outlined. Recent advances and their intended applications are also explored.