SARS-CoV-2 variants and ending the COVID-19 pandemic

[...]the end of the pandemic is only possible when vaccines that are effective against circulating variants are distributed equitably across the world. [...]for surveillance of the circulation of SARS-CoV-2 variants, sharing of variant-specific PCR primers could help to monitor their spread, particu...

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Published inThe Lancet (British edition) Vol. 397; no. 10278; pp. 952 - 954
Main Authors Fontanet, Arnaud, Autran, Brigitte, Lina, Bruno, Kieny, Marie Paule, Karim, Salim S Abdool, Sridhar, Devi
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 13.03.2021
Elsevier Limited
Elsevier
Subjects
Biological Specimen Banks
Biosurveillance
Cell-mediated immunity
Comment
Communicable Disease Control
Communicable Disease Control - methods
Coronaviruses
COVID-19
COVID-19 - transmission
COVID-19 Vaccines
COVID-19 Vaccines - therapeutic use
Databases, Genetic
Disease transmission
Functional testing
High income
Humans
Immunization
Infections
Life Sciences
Mutation
Pandemics
Proteins
Santé publique et épidémiologie
SARS-CoV-2
SARS-CoV-2 - pathogenicity
Severe acute respiratory syndrome coronavirus 2
Vaccines
Viral diseases
United Kingdom > UK
Brazil
South Africa
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Summary:[...]the end of the pandemic is only possible when vaccines that are effective against circulating variants are distributed equitably across the world. [...]for surveillance of the circulation of SARS-CoV-2 variants, sharing of variant-specific PCR primers could help to monitor their spread, particularly in resource-limited countries. [...]a central repository of samples of sera and cells from individuals with past infection or past immunisation with available COVID-19 vaccines should be established for seroneutralisation and cellular immunity functional testing against newly discovered variants.
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PMCID: PMC7906631
ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(21)00370-6