MR-ASL联合DTI评价脑瘫患儿手术前后的脑功能

目的应用3.0T磁共振动脉自旋标记（ASL）与扩散张量成像（DTI）技术研究脑瘫患儿行颈总动脉外膜交感神经网剥脱术前后脑血流量（cerebralbloodflow，CBF）及各向异性分数（fractionalanisotropy，FA）发生的变化情况。方法应用3.0T磁共振仪对30例正常儿童与30例行颈总动脉外膜交感神经网剥脱术前1周内、术后14d的单侧痉挛型脑性瘫痪患儿进行常规序列、DWI、ASL、DTI等序列扫描，应用MriCloud后处理工作站获得被检者大脑患侧额叶、颞叶、顶叶、中央前回、内囊区域、基底节、丘脑、小脑等区域的CBF值、FA值，使用配对t检验对数据进行统计学分析。结果正常儿...

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Bibliographic Details
Published in影像诊断与介入放射学 Vol. 26; no. 5; pp. 393 - 397
Main Author 禹洋;欧阳华忠;栾新平;徐敬轩;王云玲
Format Journal Article
LanguageChinese
Published 新疆医科大学第二附属医院放射科, 新疆乌鲁木齐,830063%新疆生产建设兵团第七师医院介入中心, 新疆维吾尔自治区,833200 2017
Subjects
磁共振成像;颈总动脉外膜交感神经网剥脱术;动脉自旋标记;扩散张量成像;脑瘫患儿
Cervical perivascular sympathectomy
Cerebral palsy
磁共振成像
Magnetic resonance imaging
脑瘫患儿
Arterial spin labeling
扩散张量成像
动脉自旋标记
颈总动脉外膜交感神经网剥脱术
Diffusion tensor imaging
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Summary:目的应用3.0T磁共振动脉自旋标记（ASL）与扩散张量成像（DTI）技术研究脑瘫患儿行颈总动脉外膜交感神经网剥脱术前后脑血流量（cerebralbloodflow，CBF）及各向异性分数（fractionalanisotropy，FA）发生的变化情况。方法应用3.0T磁共振仪对30例正常儿童与30例行颈总动脉外膜交感神经网剥脱术前1周内、术后14d的单侧痉挛型脑性瘫痪患儿进行常规序列、DWI、ASL、DTI等序列扫描，应用MriCloud后处理工作站获得被检者大脑患侧额叶、颞叶、顶叶、中央前回、内囊区域、基底节、丘脑、小脑等区域的CBF值、FA值，使用配对t检验对数据进行统计学分析。结果正常儿童与脑瘫患儿进行对比，脑瘫患儿患侧大脑皮质区、中央前回、基底节、内囊、小脑区运动相关区域CBF较低，差异有统计学意义；行颈总动脉外膜交感神经网剥脱术后脑瘫患儿患侧上述区域脑血流量有改善。正常儿童与脑瘫患儿进行对比，患儿患侧基底节区、豆状核、丘脑、内囊后肢区FA值较低；手术后患儿患侧基底节区、丘脑、内囊后肢较正常组的FA值有增加，差异有统计学意义。结论经磁共振ASL及DTI技术评估颈总动脉外膜交感神经网剥脱术可有效提高患儿脑血流量，改善大脑缺血缺氧状态。
Bibliography:44-1391/R
Objective To compare the changes of cerebral blood flow(CBF)and fractional anisotropy(FA)in children with cerebral palsy before and after carotid sympathetic nerve network denudation surgery by3T magnetic resonance(MR)arterial spin labeling(ASL)and diffusion tensor imaging(DTI)techniques.Methods Conventional MR imaging,diffusion-weighted imaging(DWI),ASL,and DTI were performed on30normal children as control and on30children with unilateral cerebral palsy within1week and14days after carotid sympathetic nerve network denudation using a3T MR system(Achieva/Intera,Philips).MriCloud postprocessing workstation was used to obtain the CBF and FA values of the frontal,temporal,and parietal cortex,precentral gyrus,internal capsule,basal ganglia,thalamus,and cerebellum of the affected side.Paired t test was used for statistical analysis.Results CBF of cerebral cortex,precentral gyrus,internal capsule,basal ganglia,and cerebellum was significantly lower in children with cerebral palsy than normal control.The CBF
ISSN:1005-8001
DOI:10.3969/j.issn.1005-8001.2017.05.008