Cleavage of Poly(A)-Binding Protein by Poliovirus 3C Protease Inhibits Host Cell Translation: a Novel Mechanism for Host Translation Shutoff

• Published in: Molecular and Cellular Biology Vol. 24; no. 4; pp. 1779 - 1790
• Main Authors: Kuyumcu-Martinez, N. Muge, Van Eden, Marc E., Younan, Patrick, Lloyd, Richard E.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2004; Taylor & Francis
• Subjects: 3C Viral Proteases; Catalysis; Cell Extracts; Cysteine Endopeptidases - metabolism; Eukaryotic Initiation Factor-4G; Gene Expression; HeLa Cells; Humans; initiation factor eIF-4G; Kinetics; Peptide Fragments - metabolism; Peptide Initiation Factors - metabolism; Poliovirus; Poliovirus - enzymology; poly(A)-binding protein; Poly(A)-Binding Proteins - chemistry; Poly(A)-Binding Proteins - metabolism; Protein Biosynthesis; RNA Stability; RNA, Messenger - genetics; RNA, Messenger - metabolism; Viral Proteins - metabolism
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.24.4.1779-1790.2004

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