Rapid Induction of an Immune Response in Rat Peyer's Patch after Oral Administration of Enterococcus faecalis Strain EC-12

A rapid and sharp immune response induced in Peyer's patches (PPs) by a single gavage of a heat-killed Enterococcus faecalis strain EC-12 (EC-12) was demonstrated. EC-12 was observed inside the PPs 2.5 h post administration and induction of TNF-α and CD69 gene expression was observed at the sam...

Full description

Saved in:
Bibliographic Details
Published inBioscience, biotechnology, and biochemistry Vol. 77; no. 4; pp. 863 - 866
Main Authors INOUE, Ryo, TSUKAHARA, Takamitsu, MATSUKAWA, Noriko, WATANABE, Takumi, BUKAWA, Wakoto, NAKAYAMA, Keizo, USHIDA, Kazunari
Format Journal Article
LanguageEnglish
Published England Japan Society for Bioscience, Biotechnology, and Agrochemistry 2013
Oxford University Press
Subjects
Administration, Oral
Animals
Cytokines - genetics
Cytokines - metabolism
Enterococcus faecalis
Enterococcus faecalis - physiology
Gene Expression Regulation - immunology
Hot Temperature
immune response
Immunomodulation
lactic acid bacteria
Male
Microbial Viability
Peyer's patch
Peyer's Patches - immunology
Peyer's Patches - metabolism
Peyer's Patches - microbiology
rat
Rats
Rats, Wistar
Time Factors
Online AccessGet full text

Cover

More Information
Summary:A rapid and sharp immune response induced in Peyer's patches (PPs) by a single gavage of a heat-killed Enterococcus faecalis strain EC-12 (EC-12) was demonstrated. EC-12 was observed inside the PPs 2.5 h post administration and induction of TNF-α and CD69 gene expression was observed at the same time. The immune response in PPs disappeared 24 h post administration.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.120838