Anesthetic implication of tricuspid valve replacement in a patient with acute intermittent porphyria

• Published in: Annals of cardiac anaesthesia Vol. 19; no. 2; pp. 367 - 371
• Main Authors: Saberi, Kianoush, Salehi, Mehrdad, Rahmanian, Mehrzad, Bakhshandeh, Ali, Mahlabani, Mohammad
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow Publications 01.04.2016; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Acute intermittent porphyria; Cardiac surgery; Tricuspid valve replacement surgery; Adult; Anesthesia; Anesthesia - methods; Care and treatment; Case Report; Central nervous system agents; Coronary artery bypass; Dosage and administration; Health aspects; Heart Valve Prosthesis Implantation - methods; Humans; Male; Porphyria; Porphyria, Acute Intermittent - complications; Porphyria, Acute Intermittent - therapy; Postoperative Complications - therapy; Tricuspid Valve - surgery; Tricuspid Valve Insufficiency - surgery; India
• ISSN: 0971-9784; 0974-5181
• DOI: 10.4103/0971-9784.179623

Facing a patient with acute intermittent porphyria (AIP), there is narrow safety margin which circumscribe all the therapeutic actions including choice of drugs. This would become even more complicated when it comes to a stressful and drug-dependent process like a cardiopulmonary bypass. According to author′s researches, no specific AIP case of tricuspid valve (TV) replacement is reported recently. Furthermore, fast-track anesthesia was safely used in this 37-year-old male known the case of AIP, who was a candidate for TV replacement and removing the port catheter. The patient was extubated subsequently, only 3 h after entering the Intensive Care Unit.