Adherence to hemophilia patients with prophylaxis: Veritas-Pro and psychometric properties adapted to Turkish

• Published in: PloS one Vol. 18; no. 8; p. e0288625
• Main Authors: Mehrekula Demirci, Zuhal, Demiral Yilmaz, Nilufer, Bulbul, Hale, Keklik Karadag, Fatma, Atilla, Fatos Dilan, Saydam, Guray, Sahin, Fahri
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 09.08.2023
• Subjects: Analysis; Biology and Life Sciences; Blood clot; Blood coagulation factor VIII; Care and treatment; Diagnosis; Disease prevention; Evaluation; Factor analysis; Hemophilia; Linguistics; Medical research; Medicine and Health Sciences; Medicine, Experimental; Patient compliance; Patients; Physical Sciences; Prophylaxis; Quantitative psychology; Reliability analysis; Research and Analysis Methods; Research design; Social Sciences; Thromboembolism; Thrombosis; Translation; Validation studies; Validity; Turkey
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0288625

The Validated Hemophilia Regimen Treatment Adherence Scale-Prophylaxis (VERITAS-Pro) assesses adherence to prophylaxis treatment recommendations in hemophilia patients. This study aimed to adapt the VERITAS-Pro into Turkish and evaluate its reliability and validity. The research design used is a psychometric study. A convenience sample of 102 patients with hemophilia A or B was followed by the Aegean Adult Hemophilia and Thrombosis Center. The VERITAS-Pro was adapted to Turkish in six steps, including forward- and back-translation, committee review, and reliability and validity analysis. Based on the confirmatory factor analysis, modification indices suggested discrepancies amongst items, which were improved upon the removal of items 11 and 15. Findings from this alternative model are: χ2/df = 1.34; RMSEA = 0.05; SRMR = 0.09; and IFI = 0.92. The alternative model showed high adherence rates. Cronbach's alpha value for the Turkish version was found to be 0.83. The test-retest reliability of the Turkish scale ranged from 0.31 to 0.78. All items discriminated significantly between participants who were more adherent and those who were less adherent (t = 23.53; p<0.01). Translation of the VERITAS-Pro into local languages enables more accurate measurement of treatment adherence among people with hemophilia and facilitates cross-cultural comparison studies. According to the validity and reliability evidence obtained, the psychometric properties of the Turkish version of the VERITAS-Pro are suitable.