Effect on the Duration of Mechanical Ventilation of Identifying Patients Capable of Breathing Spontaneously

For over two decades, physicians have attempted to define the best methods of discontinuing mechanical ventilation in patients recovering from respiratory failure. An early study of weaning 1 noted that the clinical decision to discontinue mechanical ventilation is often arbitrary, based on “judgmen...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 335; no. 25; pp. 1864 - 1869
Main Authors Ely, E. Wesley, Baker, Albert M, Dunagan, Donnie P, Burke, Henry L, Smith, Allen C, Kelly, Patrick T, Johnson, Margaret M, Browder, Rick W, Bowton, David L, Haponik, Edward F
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 19.12.1996
Subjects
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Critical Care - economics
Emergency and intensive respiratory care
Female
Hospital Costs
Humans
Informed consent
Intensive care medicine
Male
Medical research
Medical sciences
Middle Aged
Patients
Physicians
Proportional Hazards Models
Respiration, Artificial - economics
Respiratory Insufficiency - therapy
Survival Analysis
Time Factors
Ventilation
Ventilator Weaning - adverse effects
Ventilator Weaning - methods
Human
Coronary intensive care
Assisted ventilation
Respiratory disease
Spontaneous
Intensive care unit
Cost benefit ratio
Prevention
Randomization
Association
Lung function
Respiratory failure
Comparative study
Duration of action
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Summary:For over two decades, physicians have attempted to define the best methods of discontinuing mechanical ventilation in patients recovering from respiratory failure. An early study of weaning 1 noted that the clinical decision to discontinue mechanical ventilation is often arbitrary, based on “judgment and experience.” With increasing recognition of the risks and economic consequences of prolonged ventilation, identifying strategies that reduce the duration of mechanical ventilation remains a high priority, 2 , 3 but no single approach has been established as the best one. Many measures have been proposed to identify patients ready for extubation, 1 , 4 – 15 ranging from simple maneuvers, such as . . .
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199612193352502