A National Survey of Policies on Disclosure of Conflicts of Interest in Biomedical Research

• Published in: The New England journal of medicine Vol. 343; no. 22; pp. 1621 - 1626
• Main Authors: McCrary, S. Van, Anderson, Cheryl B, Jakovljevic, Jelena, Khan, Tonya, McCullough, Laurence B, Wray, Nelda P, Brody, Baruch A
• Format: Journal Article
• Language: English
• Published: Legacy CDMS Massachusetts Medical Society 30.11.2000
• Subjects: Academies and Institutes - organization & administration; Academies and Institutes - statistics & numerical data; Biological and medical sciences; Biomedical Research; Conflict of Interest; Conflicts of interest; Data Collection; Disclosure; Financing, Government; Government Agencies - organization & administration; Government Agencies - statistics & numerical data; Humans; Life Sciences (General); Medical ethics; Medical research; Medical schools; Medical sciences; Miscellaneous; Organizational Policy; Periodicals as Topic - statistics & numerical data; Polls & surveys; Public health. Hygiene; Public health. Hygiene-occupational medicine; Research - standards; Research Personnel - standards; Research Support as Topic; Schools, Medical - organization & administration; Schools, Medical - statistics & numerical data; United States; USA; United States; North America; America; Human; Support, U.s. Gov't, Non-P.h.s; Biomedical And Behavioral Research; Academies And Institutes/organization & Administration; Research Support; United States; Schools, Medical/organization & Administration/statistics & Numerical Data; Research Personnel/standards; Empirical Approach; Data Collection; Organizational Policy; Government Agencies/organization & Administration/statistics & Numerical Data; Financing, Government; Research/standards; Biomedical Research; Periodicals/statistics & Numerical Data; Clinical Approach/source; Conflict Of Interest; Teaching hospital; Decision making; Health; Multicenter study; Interest; Health policy; Surveillance; Conflict; Health economy; Clinical trial; Public health; Communication; Applied research; Biomedical and Behavioral Research
• ISSN: 0028-4793; 1533-4406
• DOI: 10.1056/NEJM200011303432207

Scientific misconduct involves inherently unacceptable behavior that directly threatens the integrity of research. Conflicts of interest may inappropriately influence the design, conduct, or reporting of research, thus threatening its scientific value and the rights and interests of research subjects. There has been growing concern about conflicts of interest in biomedical research. 1 – 9 The Institute of Medicine has described two opposing models for managing conflicts of interest. One model is based on the presumption that any relationships that might present a conflict must be prohibited, and the other is based on the presumption that such relationships can be handled through disclosure . . .