Primary cardiac fibrosarcoma in a dog

• Published in: Journal of Veterinary Medical Science Vol. 66; no. 8; pp. 979 - 982
• Main Authors: Madarame, H. (Azabu Univ., Sagamihara, Kanagawa (Japan). School of Veterinary Medicine), Sato, K, Ogihara, K, Ishibashi, T, Fujii, Y, Wakao, Y
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.08.2004; Japan Science and Technology Agency
• Subjects: Animals; canine; Dog Diseases - pathology; DOGS; Fibroblasts - diagnostic imaging; fibrosarcoma; Fibrosarcoma - pathology; Fibrosarcoma - veterinary; HEART; Heart Atria - pathology; Heart Neoplasms - pathology; Heart Neoplasms - veterinary; HISTOPATHOLOGY; Immunohistochemistry - veterinary; Japan; Microscopy, Electron - veterinary; SARCOMA; Ultrasonography; ULTRASTRUCTURE
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.66.979

A primary cardiac fibrosarcotna in the right atrium of a 6-year-old Chihuahua dog is described. At necropsy, there was a firm, whitish and spherical mass in the right atrium. Histopathologically. the mass had moderate cellularity composed of spindle-shaped cells with scattered multinucleated giant cells. The tumor cells were arranged in interwoven bundles and sheets in the collagenous stroma. No metastases were observed. Ultrastructurally, the tumor cells mainly consisted of fibroblasts. Multinuclealed giant cells did not have any certain organelles that would indicate a higher order of differentiation. Primary cardiac sarcomas in dogs are extremely rare.