1250-P: Clinical and Demographic Characteristics of Patients with Coexistent Type 2 Diabetes, Hypertension, and Dyslipidemia—Results from the Largest Retrospective EMR Study from India

Introduction: Common manifestations of end-organ damage due to diabetes, dyslipidemia and hypertension, predispose patients to develop cardiovascular diseases (CVD). The data on triple disease in India is scarce. In patients with triple disease, CVD risk is amplified, necessitating better understand...

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Published inDiabetes (New York, N.Y.) Vol. 72; no. Supplement_1; p. 1
Main Authors NATARAJAN, VIDHYA, CHAWLA, RAJEEV, DALAL, JAMSHED, CHANDRA, PRAVEEN, KUMAR, VIVEKA, AYYAR, VAGEESH, BADANI, RAJESH S., HUSSAIN NAQVI SYED, MUJTABA, GAURAV, KUMAR, DHANAKI, GAURI D., RATHOD, RAHUL T., KOTAK, BHAVESH P.
Format Journal Article
LanguageEnglish
Published New York American Diabetes Association 20.06.2023
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Summary:Introduction: Common manifestations of end-organ damage due to diabetes, dyslipidemia and hypertension, predispose patients to develop cardiovascular diseases (CVD). The data on triple disease in India is scarce. In patients with triple disease, CVD risk is amplified, necessitating better understanding of their current clinical characteristics and care gaps. Aims and Methods: This was an EMR based, retrospective, multicenter, cross sectional, database study to evaluate the demographic and clinical profile of adult patients with age more than 18 years having coexistent type 2 DM, dyslipidemia, and hypertension in India. Data of patients with type 1 DM, FH and pregnancy were excluded. Results: Data of 6722173 patients with age ≥18 years registered in EMR from Jan ‘21 to Dec ‘21 was extracted from the EMR database. Out of these patients, 427835 (6.36%) were found to have coexistent hypertension, type 2 DM and dyslipidemia. Mean age was 59.92 years and 57% were males. The mean BMI was 28.07 kg/m2, and 73% had an above normal BMI (>24.99). The mean SBP and DBP in mmHg were noted to be 138.81 and 82.17, respectively. Only 10% and 28% of patients had a normal SBP and normal DBP, respectively. The mean HbA1c was 8.35% with only 27% having HbA1C <7%. The mean (% optimal control) LDL, total cholesterol, triglycerides in mg/dl (%) was 98.38 (44), 174.75 (28), and 181.42 (56), respectively. ARBs (25%) and combination of anti-hypertensive with diuretics (14%) were most used for hypertension treatment. Statin alone was used in 38% of patients while statin in combination with other drugs was used in 56%. Biguanides alone and its combination with sulphonylureas were used in 74.6% and 41% of patients with diabetes, respectively. Conclusion: The findings suggests that control of triple disease in India is inadequate despite therapy. There is need to optimize management of triple disease. Disclosure V.Natarajan: Employee; Dr. Reddy’s Laboratories Ltd. G.D.Dhanaki: None. R.T.Rathod: None. B.P.Kotak: Employee; Dr. Reddy’s Laboratories Ltd. R.Chawla: None. J.Dalal: None. P.Chandra: None. V.Kumar: None. V.Ayyar: None. R.S.Badani: None. M.Syed: None. K.Gaurav: None.
ISSN:0012-1797
1939-327X
DOI:10.2337/db23-1250-P