101例埃索美拉唑不良反应文献分析

目的：了解埃索美拉唑引发药品不良反应（adverse drug reaction,ADR）的情况,为临床合理用药提供参考。方法：以＂埃索美拉唑＂＂esomeprazole＂为关键词,检索1995—2015年中国医院数字图书馆期刊全文数据库、万方数据库、维普数据库和Pubmed医学文献检索系统中有关埃索美拉唑致ADR的文献,并对患者的性别、年龄、ADR出现时间、ADR累及器官和（或）系统与临床表现、解救措施以及转归情况进行统计分析。结果：共检索到101例相关病例。埃索美拉唑致ADR多发生在60~79岁年龄段,占53.47%;ADR可累及多个器官和（或）系统,主要为消化系统（33.66%）和泌尿系...

Full description

Saved in:
Bibliographic Details
Published in中国医院用药评价与分析 Vol. 16; no. 4; pp. 546 - 548
Main Author 倪倍倍 刘晓英 乔伟立 毕鹏飞 代梦 殷衍磊 于江州 李静
Format Journal Article
LanguageChinese
Published 青岛大学附属医院药学部,山东青岛,266000 2016
Subjects
埃索美拉唑
文献分析
药品不良反应
文献分析
埃索美拉唑
药品不良反应
Adverse drug reaction
Esomeprazole
Literature analysis
Online AccessGet full text
ISSN1672-2124
DOI10.14009/j.issn.1672-2124.2016.04.043

Cover

More Information
Summary:目的：了解埃索美拉唑引发药品不良反应（adverse drug reaction,ADR）的情况,为临床合理用药提供参考。方法：以＂埃索美拉唑＂＂esomeprazole＂为关键词,检索1995—2015年中国医院数字图书馆期刊全文数据库、万方数据库、维普数据库和Pubmed医学文献检索系统中有关埃索美拉唑致ADR的文献,并对患者的性别、年龄、ADR出现时间、ADR累及器官和（或）系统与临床表现、解救措施以及转归情况进行统计分析。结果：共检索到101例相关病例。埃索美拉唑致ADR多发生在60~79岁年龄段,占53.47%;ADR可累及多个器官和（或）系统,主要为消化系统（33.66%）和泌尿系统（12.87%）。结论：临床应重视埃索美拉唑所致ADR,以确保用药安全。
Bibliography:NI Beibei;LIU Xiaoying;QIAO Weili;BI Pengfei;DAI Meng;YIN Yanlei;YU Jiangzhou;LI Jing;Dept.of Pharmacy,the Affiliated Hospital of Qingdao University; Shandong Qingdao 266000, China
OBJECTIVE：To investigate the adverse drug reaction（ADR） induced by esomeprazole,and provide reference for the rational drug use in clinic.METHODS：To set＂esomeprazole＂as the key words,literatures related to ADR induced by esomeprazole in CHDL,Wanfang,VIP database and Pubmed during 1995-2015 were retrieved,statistical analysis was conducted on the patients＇ gender,age,occurrence time of ADR,ADR-involved organs and systems and clinical manifestations,rescue measures and prognosis.RESULTS：Totally 101 cases were retrieved.ADR induced by esomeprazole most were seen during 60-79 years old（53.47%）;ADR can involve multiple organs and（or） systems,mainly manifested as digestive system reaction（33.66%） and urinary system（12.87%）.CONCLUSIONS：Great importance should be attached to ADR monitoring,so as to ensure the medication safety.
Esomeprazole;
ISSN:1672-2124
DOI:10.14009/j.issn.1672-2124.2016.04.043