Successful Use of Risperidone, Trihexyphenidyl, and Paroxetine in Pregnancy

A 25-year-old female patient with diagnosis of paranoid schizophrenia since 2009 was on treatment from our department since 2012, and she was showing significant improvement on maintenance dose of fixed-dose combination of Risperidone 3mg plus Trihexyphenidyl 2 mg one tablet at night. [...]she recei...

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Bibliographic Details
Published inIndian journal of psychological medicine Vol. 39; no. 6; pp. 835 - 836
Main Authors Goyal, Sandeep Kumar, Goel, Atul
Format Journal Article
LanguageEnglish
Published New Delhi, India SAGE Publications 01.11.2017
Sage Publications Ltd. (UK)
Sage Publications, New Delhi India
Medknow Publications & Media Pvt Ltd
SAGE Publishing
Subjects
Antidepressants
Antipsychotics
Birth defects
Care and treatment
Health risk assessment
Letters to Editor
Paroxetine
Pregnancy
Pregnant women
Psychotropic drugs
Risperidone
Schizophrenia
Systematic review
Trihexyphenidyl
Women's health
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Summary:A 25-year-old female patient with diagnosis of paranoid schizophrenia since 2009 was on treatment from our department since 2012, and she was showing significant improvement on maintenance dose of fixed-dose combination of Risperidone 3mg plus Trihexyphenidyl 2 mg one tablet at night. [...]she received Risperidone and Trihexyphenidyl throughout the pregnancy and paroxetine for approximately 2 months ( first trimester) Discussion Risperidone exposure is found to cause fetal malformations including Ivemark syndrome, Pierre-Robin syndrome, cardiomyopathy, cleft lip and palate, ear abnormalities, gastroschisis, gestational diabetes, and Turners' syndrome. First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0253-7176
0975-1564
DOI:10.4103/IJPSYM.IJPSYM_380_17