Optimal utilization of prevention of mother-to-child transmission of HIV services among adolescents under group versus focused antenatal care in Eastern Uganda

• Published in: PloS one Vol. 17; no. 11; p. e0275905
• Main Authors: Akunzirwe, Rebecca, Bakeera-Kitaka, Sabrina, Kalyango, Joan N, Zalwango, Jane Frances, Ssemasaazi, Judith Amutuhaire, Okello, Tom, Buhuguru, Remmy, Kiguli, Sarah, Mubuuke, Aloysius G, Ononge, Sam
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.11.2022; Public Library of Science (PLoS)
• Subjects: Adolescent; Adolescents; Antiretroviral agents; Antiretroviral therapy; Babies; Biology and Life Sciences; Births; Breastfeeding & lactation; Chemotherapy; Children & youth; Clinics; Counseling; Cross-Sectional Studies; Data collection; Disease transmission; Female; Health care; Health care facilities; Health facilities; Health services; HIV; HIV (Viruses); HIV Infections - drug therapy; Hospital facilities; Human immunodeficiency virus; Humans; Immunization; Infant; Infectious Disease Transmission, Vertical - prevention & control; Medical care; Medical tests; Medicine and Health Sciences; Mothers; People and Places; Pregnancy; Pregnancy Complications, Infectious - drug therapy; Prenatal Care; Prevention; Questionnaires; Sample size; Statistical analysis; Teenage parents; Teenagers; Uganda; Utilization; Womens health; Uganda
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0275905

Group antenatal care (G-ANC), an alternative to focused ANC (F-ANC), involves grouping mothers by gestational and maternal age. In high-income countries, G-ANC has been associated with improved utilization of health care services like Prevention of Mother to Child Transmission (PMTCT) of HIV services. Some low-resource countries with poor utilization of health care services have piloted G-ANC. However, there is limited evidence of its efficiency. We, therefore, compared G-ANC versus F-ANC with regards to optimal utilization of PMTCT of HIV services and assessed associated factors thereof among adolescent mothers in eastern Uganda. We defined optimal utilization of PMTCT of HIV services as the adolescent being up to date with HIV counseling and testing. If found HIV negative, subsequent timely re-testing. If found HIV positive, initiation of antiretroviral therapy (ART) under option B plus for the mother. While for the infant, it entailed safe delivery, testing, feeding, and appropriate HIV chemotherapy. From February to April 2020, we conducted a cross-sectional study among 528 adolescent mothers in four sites in eastern Uganda. We assessed the optimal utilization of PMTCT of HIV services among adolescent mothers that had attended G-ANC versus F-ANC at the post-natal care or immunization clinics. We also assessed the factors associated with optimal utilization of PMTCT of HIV services among these mothers. Optimal utilization of PMTCT was higher among those in G-ANC than in F-ANC (74.7% vs 41.2, p-0.0162). There was a statistically significant association between having attended G-ANC and optimal utilization of PMTCT [PR = 1.080, 95%CI (1.067-1.093)]. Other factors independently associated with optimal utilization were; having a partner that tested for HIV [PR = 1.075, 95%CI (1.048-1.103)], trimester of first ANC visit: second trimester [PR = 0.929, 95%CI (0.902-0.957)] and third trimester [PR = 0.725, 95%CI (0.616-0.853)], and the health facility attended: Bugembe HCIV [PR = 1.126, 95%CI (1.113-1.139)] and Jinja regional referral hospital [PR = 0.851, 95%CI (0.841-0.861]. Adolescent mothers under G-ANC had significantly higher optimal utilization of PMTCT of HIV services compared to those under F-ANC. We recommend that the Ministry of Health considers widely implementing G-ANC, especially for adolescent mothers.