Idiopathic thrombocytopenia in Japanese black cattle

• Published in: Journal of Veterinary Medical Science Vol. 64; no. 1; pp. 87 - 89
• Main Authors: Yasuda, J. (Iwate Univ., Morioka (Japan). Faculty of Agriculture), Okada, K, Sato, J, Sato, R, Tachibana, Y, Takashima, K, Naito, Y
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.01.2002; Japan Science and Technology Agency
• Subjects: Animals; Antibodies, Anti-Idiotypic - blood; Blood Coagulation Tests - veterinary; BLOOD DISORDERS; BONE MARROW; CATTLE; Cattle Diseases - blood; Cattle Diseases - pathology; Cattle Diseases - therapy; Conjunctival Diseases - pathology; Conjunctival Diseases - therapy; Conjunctival Diseases - veterinary; DIAGNOSIS; Fatal Outcome; Female; Hematoma - pathology; Hematoma - therapy; Hematoma - veterinary; Hemorrhage - veterinary; idiopathic thrombocytopenia; Thrombocytopenia - pathology; Thrombocytopenia - therapy; Thrombocytopenia - veterinary; Vaginal Diseases - pathology; Vaginal Diseases - therapy; Vaginal Diseases - veterinary
• ISSN: 0916-7250; 1347-7439
• DOI: 10.1292/jvms.64.87

A female Japanese Black cow showed hemorrhage under the mucous membrane of the eye conjunctiva and the vagina, and thrombocytopenia in peripheral blood. The clinical manifestations repeated spontaneously during long-term observation. The clinical findings were stable except for severe periodic bleeding. Prothrombin time, activated partial thromboplastin time and fibrinogen levels were normal. The anti-platelet antibody in the serum was analyzed by indirect platelet coagulation tests. Because the platelets in themicro- plate wells of the subject series showed coagulation up to 1:128, it was judged that anti-platelet antibody was present in the serum. A number of megakaryocytes were recognized in smear samples obtained from bone marrow of the scapula immediately after euthanasia. Therefore, this case was diagnosed as idiopathic thrombocytopenia.