The History of Methicillin-Resistant Staphylococcus aureus in Brazil

Since the emergence of MRSA in the 1960s, a gradual increase in infections by resistant bacteria has been observed. Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance. The high adaptability and pathogenic profile o...

Full description

Saved in:
Bibliographic Details
Published inThe Canadian journal of infectious diseases & medical microbiology Vol. 2020; no. 2020; pp. 1 - 18
Main Authors Amorim, Jaime Henrique, da Silva Oliveira Souza, Rayane, Luiz, Wilson Barros, Andrade, Mariana Moreira
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 07.10.2020
Hindawi
Hindawi Limited
Wiley
Subjects
Adaptability
Antibiotics
Antimicrobial agents
Bacteria
Causes of
Chromosomes
Cloning
Distribution
Drug resistance in microorganisms
Epidemics
Genetic aspects
Identification and classification
Infectious diseases
Methicillin
Multidrug resistance
Natural history
Nosocomial infections
Pandemics
Penicillin
Public health
Review
Risk analysis
Risk factors
Staphylococcus aureus
Staphylococcus aureus infections
Staphylococcus infections
Statistics
Virulence
Brazil
Rio de Janeiro Brazil
Latin America
Online AccessGet full text

Cover

More Information
Summary:Since the emergence of MRSA in the 1960s, a gradual increase in infections by resistant bacteria has been observed. Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance. The high adaptability and pathogenic profile of MRSA clones contributed to its spread in hospital and community settings. In Brazil, the first MRSA isolates were reported in the late 1980s, and since then different genetic profiles, such as the Brazilian epidemic clone (BEC) and other clones considered a pandemic, became endemic in the Brazilian population. Additionally, Brazil’s MRSA clones were shown to be able to transfer genes involved in multidrug resistance and enhanced pathogenic properties. These events contributed to the rise of highly resistant and pathogenic MRSA. In this review, we present the main events which compose the history of MRSA in Brazil, including numbers and locations of isolation, as well as types of staphylococcal cassette chromosome mec (SCCmec) found in the Brazilian territory.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Academic Editor: Peter J. Weina
ISSN:1712-9532
1918-1493
DOI:10.1155/2020/1721936