Low occurrence of extended-spectrum cephalosporinase producing Enterobacteriaceae and no detection of methicillin-resistant coagulase-positive staphylococci in healthy dogs in Sweden

• Published in: Acta veterinaria scandinavica Vol. 62; no. 1; p. 18
• Main Authors: Börjesson, Stefan, Gunnarsson, Lotta, Landén, Annica, Grönlund, Ulrika
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 25.04.2020; BioMed Central; BMC
• Subjects: Animals; Antibiotic resistance; Antibiotics; Bacteria; Beta lactamases; bla CMY-2; bla CTX-M; blaCMY-2; blaCTX-M; Blood & organ donations; Brief Communication; Canine; Cephalosporinase; Coagulase; Dogs; Drug resistance; E coli; Enterobacteriaceae; ESBL; Escherichia coli; Methicillin; Microbial drug resistance; MRSA; MRSP; Multidrug resistance; pAmpC; Plasmids; Poultry; S. aureus; S. pseudintermedius; Staphylococcus aureus; Staphylococcus infections; Studies; β Lactamase; Sweden; Netherlands; blaCTX-M; S. aureus; blaCMY-2; MRSP; pAmpC; MRSA; ESBL; S. pseudintermedius; E. coli; Canine; Enterobacteriaceae; bla(CMY-2); pseudintermedius; E; coli; aureus; S; bla(CTX-M)
• ISSN: 1751-0147; 0044-605X; 1751-0147
• DOI: 10.1186/s13028-020-00516-4

Sweden has a long tradition of monitoring occurrence of antibiotic resistant bacteria in both animals and humans, but there currently is no organised and harmonized monitoring on carriage of Enterobacteriaceae producing extended-spectrum beta-lactamase (ESBL), plasmid-mediated AmpC beta-lactamase (pAmpC), or methicillin-resistant coagulase positive staphylococci e.g. methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus pseudintermedius (MRSP) in dogs. The aim of the current study was therefore to determine the prevalence of ESBL/pAmpC producing Enterobacteriaceae and methicillin-resistant coagulase positive staphylococci in healthy dogs in Sweden, and to phenotypically and genotypically characterize any identified isolates. It was shown that 0.9% (95% confident interval 0.3-2.7%) of the dogs (n = 325) carried multi-resistant ESBL-producing Escherichia coli, but that no methicillin-resistant coagulase positive staphylococci could be detected. In conclusion, the occurrence of multi-drug resistant bacteria remains rare among healthy dogs in Sweden. In addition, the ESBL-producing E. coli identified showed genetic characteristics related to those reported from humans.