The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources

The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building ba...

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Published inMammalian genome Vol. 26; no. 9-10; pp. 448 - 455
Main Authors Eppig, Janan T., Motenko, Howie, Richardson, Joel E., Richards-Smith, Beverly, Smith, Cynthia L.
Format Journal Article Book Review
LanguageEnglish
Published New York Springer US 01.10.2015
Springer Nature B.V
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Abstract The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.
AbstractList The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.
Issue Title: Special Issue: Informatics and Integrative Genomics - Part 2 The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.
Author Richardson, Joel E.
Smith, Cynthia L.
Richards-Smith, Beverly
Eppig, Janan T.
Motenko, Howie
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  givenname: Howie
  surname: Motenko
  fullname: Motenko, Howie
  organization: Mouse Genome Informatics, The Jackson Laboratory
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  givenname: Joel E.
  surname: Richardson
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  organization: Mouse Genome Informatics, The Jackson Laboratory
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  surname: Richards-Smith
  fullname: Richards-Smith, Beverly
  organization: Mouse Genome Informatics, The Jackson Laboratory
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  givenname: Cynthia L.
  surname: Smith
  fullname: Smith, Cynthia L.
  organization: Mouse Genome Informatics, The Jackson Laboratory
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26373861$$D View this record in MEDLINE/PubMed
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Mouse Genome Database
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Snippet The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice...
Issue Title: Special Issue: Informatics and Integrative Genomics - Part 2 The availability of and access to quality genetically defined, health-status known...
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StartPage 448
SubjectTerms Animal Genetics and Genomics
Animals
Biomedical and Life Sciences
Biomedical Research
Cataloging
Cell Biology
Cell Line - classification
Embryonic Stem Cells - classification
Human Genetics
Humans
Internet
Life Sciences
Mice
Mice, Inbred Strains - classification
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Title The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources
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