The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources
The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building ba...
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Published in | Mammalian genome Vol. 26; no. 9-10; pp. 448 - 455 |
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Main Authors | , , , , |
Format | Journal Article Book Review |
Language | English |
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New York
Springer US
01.10.2015
Springer Nature B.V |
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Abstract | The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs. |
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AbstractList | The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs. Issue Title: Special Issue: Informatics and Integrative Genomics - Part 2 The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs. |
Author | Richardson, Joel E. Smith, Cynthia L. Richards-Smith, Beverly Eppig, Janan T. Motenko, Howie |
Author_xml | – sequence: 1 givenname: Janan T. surname: Eppig fullname: Eppig, Janan T. email: janan.eppig@jax.org organization: Mouse Genome Informatics, The Jackson Laboratory – sequence: 2 givenname: Howie surname: Motenko fullname: Motenko, Howie organization: Mouse Genome Informatics, The Jackson Laboratory – sequence: 3 givenname: Joel E. surname: Richardson fullname: Richardson, Joel E. organization: Mouse Genome Informatics, The Jackson Laboratory – sequence: 4 givenname: Beverly surname: Richards-Smith fullname: Richards-Smith, Beverly organization: Mouse Genome Informatics, The Jackson Laboratory – sequence: 5 givenname: Cynthia L. surname: Smith fullname: Smith, Cynthia L. organization: Mouse Genome Informatics, The Jackson Laboratory |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26373861$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/j.molbrainres.2004.09.016 10.1038/78146 10.1016/S0168-9525(98)01665-5 10.1093/nar/gki113 10.5483/BMBRep.2012.45.12.242 10.1093/nar/gkp799 10.1007/s00335-012-9428-9 10.1007/s00335-012-9427-x 10.1186/s13059-015-0653-x 10.1534/genetics.114.169771 10.1093/hmg/8.10.1955 10.1007/s003350010096 10.1186/1756-0500-5-577 10.1038/nature14269 |
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SubjectTerms | Animal Genetics and Genomics Animals Biomedical and Life Sciences Biomedical Research Cataloging Cell Biology Cell Line - classification Embryonic Stem Cells - classification Human Genetics Humans Internet Life Sciences Mice Mice, Inbred Strains - classification |
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Title | The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources |
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