The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources

The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building ba...

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Bibliographic Details
Published inMammalian genome Vol. 26; no. 9-10; pp. 448 - 455
Main Authors Eppig, Janan T., Motenko, Howie, Richardson, Joel E., Richards-Smith, Beverly, Smith, Cynthia L.
Format Journal Article Book Review
LanguageEnglish
Published New York Springer US 01.10.2015
Springer Nature B.V
Subjects
Animal Genetics and Genomics
Animals
Biomedical and Life Sciences
Biomedical Research
Cataloging
Cell Biology
Cell Line - classification
Embryonic Stem Cells - classification
Human Genetics
Humans
Internet
Life Sciences
Mice
Mice, Inbred Strains - classification
Repository Site
Cryopreserved Embryo
Informatics Infrastructure
International Mouse Phenotyping Consortium
Mouse Genome Database
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Summary:The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.
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ISSN:0938-8990
1432-1777
DOI:10.1007/s00335-015-9600-0