The Psychiatric GWAS Consortium: Big Science Comes to Psychiatry

The Psychiatric GWAS Consortium was founded with the aim of conducting statistically rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders: ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia. In the era of GWAS and high-throughput genomics, a ma...

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Bibliographic Details
Published inNeuron (Cambridge, Mass.) Vol. 68; no. 2; pp. 182 - 186
Main Author Sullivan, Patrick F.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 21.10.2010
Elsevier Limited
Subjects
Attention deficit hyperactivity disorder
Bipolar disorder
Genes
Genome-Wide Association Study - history
Genome-Wide Association Study - trends
Genomics
History, 20th Century
History, 21st Century
Humans
Medicin och hälsovetenskap
Mental Disorders - diagnosis
Mental Disorders - genetics
Mental Disorders - therapy
Meta-Analysis as Topic
Neurobiology - history
Neurobiology - methods
Neurobiology - trends
Neurosciences
Psychiatry - methods
Psychiatry - trends
Studies
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Summary:The Psychiatric GWAS Consortium was founded with the aim of conducting statistically rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders: ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia. In the era of GWAS and high-throughput genomics, a major trend has been the emergence of collaborative, consortia approaches. Taking advantage of the scale that collaborative consortia approaches can bring to a problem, the PGC has been a major driver in psychiatric genetics and provides a model for how similar approaches may be applied to other disease communities.
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ISSN:0896-6273
1097-4199
1097-4199
DOI:10.1016/j.neuron.2010.10.003