Periodontal cell mechanotransduction

The periodontium is a structurally and functionally complex tissue that facilitates the anchorage of teeth in jaws. The periodontium consists of various cell types including stem cells, fibroblasts and epithelial cells. Cells of the periodontium are constantly exposed to mechanical stresses generate...

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Bibliographic Details
Published inOpen biology Vol. 8; no. 9
Main Authors Chukkapalli, Sasanka S., Lele, Tanmay P.
Format Journal Article
LanguageEnglish
Published England The Royal Society 01.09.2018
Subjects
Cell Shape
Cytoskeleton
Mechanobiology
Mechanotransduction
Periodontal Disease
Review
Traction Force
mechanobiology
traction force
cell shape
cytoskeleton
mechanotransduction
periodontal disease
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Summary:The periodontium is a structurally and functionally complex tissue that facilitates the anchorage of teeth in jaws. The periodontium consists of various cell types including stem cells, fibroblasts and epithelial cells. Cells of the periodontium are constantly exposed to mechanical stresses generated by biological processes such as the chewing motions of teeth, by flows generated by tongue motions and by forces generated by implants. Mechanical stresses modulate the function of cells in the periodontium, and may play a significant role in the development of periodontal disease. Here, we review the literature on the effect of mechanical forces on periodontal cells in health and disease with an emphasis on molecular and cellular mechanisms.
Bibliography:ObjectType-Article-2
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ISSN:2046-2441
2046-2441
DOI:10.1098/rsob.180053